Kinetic properties of cobalt-iron hybrid hemoglobins
نویسندگان
چکیده
منابع مشابه
Allosteric transitions in cobalt hemoglobins.
Circular dichroism and difference ultraviolet visible spectra were obtained for cobalt hemoglobin derivatives. At 287 nm the ellipticity difference between the oxy- and deoxycobaltohemoglobin is about one-half as great as that for the native proteins indicating smaller quaternary conformational changes for the former. Deoxygenation increases the Soret rotational strengths of both iron and cobal...
متن کاملStudies on Cobalt Myoglobins and Hemoglobins
The reversible oxygenation equilibrium of cobalt myoglobins and hemoglobins, complexes of apomyoglobin and apohemoglobin with cobaltous proto-, meso-, and deuteroporphyrins IX (proto-, meso-, and deutero-CoMb and -CoHb) has been investigated kinetically by the temperature jump relaxation method. The following association and dissociation rate constants (k,, and iz& were obtained in 0.1 M phosph...
متن کاملStudies on cobalt myoglobins and hemoglobins. I. Preparation and optical properties of myoglobins and hemoglobins containing cobalt proto-, meso-, and deuteroporphyrins and thermodynamic characterization of their reversible oxygenation.
Artificial myoglobins and hemoglobins containing cobaltous proto-, meso-, and deuteroporphyrins (proto-, meso-, and deutero-CoMb and -CoHb) have been prepared reproducibly by an anaerobic recombination of apomyoglobin from sperm whale and apohemoglobin from human blood with cobaltous porphyrins in the presence of pyridine. These CoMb and CoHb contain one cobalt porphyrin per heme binding site a...
متن کاملStudies on Cobalt Myoglobins and Hemoglobins
The reversible oxygenation equilibrium of cobalt myoglobins and hemoglobins, complexes of apomyoglobin and apohemoglobin with cobaltous proto-, meso-, and deuteroporphyrins IX (proto-, meso-, and deutero-CoMb and -CoHb) has been investigated kinetically by the temperature jump relaxation method. The following association and dissociation rate constants (k,, and iz& were obtained in 0.1 M phosph...
متن کاملStudies on Cobalt Myoglobins and Hemoglobins I. PREPARATION AND OPTICAL PROPERTIES OF MYOGLOBINS AND HEMOGLOBINS CONTAINING COBALT PROTO-, MESO-, AND DEUTEROPORPHYRINS
Artificial myoglobins and hemoglobins containing cobaltous proto-, meso-, and deuteroporphyrins (proto-, meso-, and deutero-CoMb and -CoHb) have been prepared reproducibly by an anaerobic recombination of apomyoglobin from sperm whale and apohemoglobin from human blood with cobaltous porphyrins in the presence of pyridine. These CoMb and CoHb contain one cobalt porphyrin per heme binding site a...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1983
ISSN: 0014-5793
DOI: 10.1016/0014-5793(83)80150-1